AIM: To evaluate the efficacy of including cytoflavin in rehabilitation measures in the early recovery period of patients with ischemic stroke. MATERIAL AND METHODS: Results of rehabilitation measures of 100 patients (50 women and 50 men, aged 18 to 85 years) in the early recovery period of ischemic stroke were analyzed. Psychological testing included NIHSS, MMSE, Rankin scale, Rivermead mobility index, exercise tolerance test. Depending on the rehabilitation scheme, patients were divided into the main group (n=50), who received a verticalization course and cytoflavin (intravenously, drip 20.0 ml in 250.0 ml 5% glucose for 14 days). The control group (n=50) included patients who received standard treatment. RESULTS AND CONCLUSION: Inclusion of cytoflavin in the rehabilitation scheme for patients with ischemic stroke increased the effectiveness of treatment, which was manifested by a decrease in the severity of neurological disorders assessed with NIHSS by 17.6% in the main group versus 10.8% in the control group (p<0.05) and recovery of cognitive functions assessed with MMSE by 5.8% versus 1.6%, respectively (p<0.05). In addition, there was a positive dynamics in the restoration of blood pressure (by 37.1% in the main group versus 30.6% in the control group (p<0.05)).
Brain Ischemia/therapy , Stroke Rehabilitation , Stroke/therapy , Adolescent , Adult , Aged , Aged, 80 and over , Blood Pressure/drug effects , Brain Ischemia/metabolism , Cognition/drug effects , Drug Combinations , Female , Flavin Mononucleotide/administration & dosage , Flavin Mononucleotide/pharmacology , Flavin Mononucleotide/therapeutic use , Humans , Inosine Diphosphate/administration & dosage , Inosine Diphosphate/pharmacology , Inosine Diphosphate/therapeutic use , Male , Middle Aged , Niacinamide/administration & dosage , Niacinamide/pharmacology , Niacinamide/therapeutic use , Stroke/metabolism , Succinates/administration & dosage , Succinates/pharmacology , Succinates/therapeutic use , Treatment Outcome , Young Adult
We studied the vascular endothelial vasomotor function in healthy young individuals, depending on the type of character accentuation, levels of neuroticism, depression and anxiety. It is shown that the types of character accentuation effect on endothelial vasomotor function in healthy men and women. Personality characteristics of a person can be a significant risk factor for disease, the pathogenesis of which is the starting element of endothelial vasomotor dysfunction.
Anxiety/physiopathology , Character , Depression/physiopathology , Endothelium, Vascular/physiopathology , Neurotic Disorders/physiopathology , Vasomotor System/physiopathology , Adult , Anxiety/psychology , Blood Flow Velocity/physiology , Depression/psychology , Endothelium, Vascular/innervation , Female , Humans , Laser-Doppler Flowmetry , Male , Neurotic Disorders/psychology , Personality Assessment , Psychometrics , Vasodilation/physiology , Young Adult
